Nir Research Group
DNA Nanomachine Lab
Ben Gurion University of the Negev
Prof. Eyal Nir - Head of the Lab
I joined the department of chemistry at BGU in October 2008 after returning to Israel from my postdoctoral studies at the University of California Los-Angeles (UCLA). My interests are in the area of the structure, dynamics, interaction, and function of Biomolecules, especially proteins and DNA, aiming for a detailed molecular-level understanding of the mechanisms that govern biological processes, and in DNA nanotechnology, aiming for the development of reliable DNA based technology, especially motors. To achieve this goal, we are implementing a novel single-molecule fluorescence approach that uses Fluorescence Resonance Energy Transfer (sm-FRET) and Alternating Laser Excitation (ALEX) techniques. These methods were developed, including by me, in my postdoctoral lab under the supervision of Professor Shimon Weiss.
Dr. Maria Popov - Lab manager
Researcher and Lab manager of two labs. Hence, two directions of research, somehow "crosslinked" by studies in the field of single-molecule fluorescence. In Eyal Nir's lab, it is construction Former activities of molecular machines (rotors). Also, running all possible (and impossible, such as high NaCl content) types of gel electrophoresis for the lab members, and doing all kinds of origami purification.: Ph.D. (Faculty of the Health Sciences, BGU) and research in the area of DDS (drug delivery systems), including in vitro (cell culture, histology, flow cytometry, confocal fluorescent microscopy, etc.) and in vivo studies (animal models, PK studies)
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Breveruos Sheheade - Ph.D. student
2015-2019: Combined Bachelor's dual degree in Chemistry and Chemical Engineering.
2019: Started Ph.D. as Direct track student currently working on the development of a robust autonomous rotatory motor made out of DNA origami-based structure
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Haggai Shapira - Ph.D. student
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I love to learn about nature. I completed my bachelor's degree in chemistry and computer science at BGU, and currently, I am studying for a master's degree in the group. I think making molecular machines is a top goal for science and that it is very cool. My subject of research is a DNA-based rotor. I also work on the programming aspect of analyzing the rotation of a gold-connected-rotor from a stream of defocused images taken in the new setup, possibly using AI and other programming issues.
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Alumni
Roman Tsukanov - Ph.D.
Miran Liber - Ph.D.
Yaron Berger - Ph.D.
Ofir Perel - M.Sc.
Toma E. Tomov - Ph.D.
Rula Masoud - M.Sc.
Dinesh C. Khara - Post.Doc.
Meitar Uralevitch - M.Sc.
Noa Plavner Hazan - Ph.D.
Hadas Volkov - M.Sc.
Samrat Basak - Ph.D.